Principal Clinical Scientist

Principal Clinical Scientist (AI Training)

About The Role

What if your expertise in clinical trial design and regulatory science could directly influence how AI reasons about medicine, evidence, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level clinical expertise into the heart of cutting-edge AI development — ensuring that the systems shaping the future of biomedical research are grounded in real-world scientific rigor.

This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work at the intersection of medicine and artificial intelligence.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulatory-ready datasets for AI training and evaluation
• Interpret and audit clinical trial results, ensuring accuracy, consistency, and alignment with regulatory standards
• Evaluate AI-generated clinical analyses for scientific soundness and adherence to FDA, EMA, or equivalent regulatory expectations
• Provide expert, structured feedback that directly improves how AI models understand and reason about clinical trial data and outcomes
• Help bridge the gap between frontier AI systems and the rigorous standards of real-world clinical research

Who You Are

• Senior-level clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission
• Deep expertise interpreting clinical data for major regulatory agencies — FDA, EMA, or equivalent
• Strong foundation in clinical research methodology, biostatistics, translational science, or a closely related discipline
• Naturally detail-oriented with a systematic, methodical approach to evaluating complex scientific information
• Comfortable working independently and asynchronously in a remote environment

Nice to Have

• Prior experience with data annotation, data quality assurance, or AI evaluation workflows
• Background in pharmacology, medical writing, or clinical affairs
• Familiarity with AI tools or content evaluation platforms

Why Join Us

• Work directly on frontier AI systems that are reshaping clinical and biomedical research
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with meaningful, high-impact task-based work
• Influence how AI understands, evaluates, and communicates real-world clinical evidence
• Collaborate with world-leading AI research teams and labs
• Potential for ongoing work and contract extension as new projects launch